What are the dangers of MDMA?

topic posted Mon, June 15, 2009 - 7:17 PM by  Hanzi
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Is there a safe amount or frequency? What are long term effects?
posted by:
Hanzi
Maryland
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  • B-b
    B-b
    offline 7

    Re: What are the dangers of MDMA?

    Mon, June 15, 2009 - 7:52 PM
    Long term effects would take some research to explain. One of the things I have noticed over the years is that it overheats the body, so can lead to excessive activity, and thereby dehydration. I never took much of it, back in my day. It's a body-high drug, not a mental high drug, in my estimation. Like mushrooms and acid are most mental-high drugs, affecting mostly the brain, while having some bodily effects, in my experience.

    I find it funny that the street drug market is flooded with body-high drugs (cocaine, speed, ecstacy, so on), and the more psychedelics (I admit that MDMA straddles those two categories), which are largely non-addicitve (LSD, Psilocybin, THC) are harder to get. I often find that the more body-high drugs have a sexual quotient to them. I never thought about sex much while on THC or LSD. Largely non-existent effects, at least for me. Yet in some ways these mental-high drugs seem more dangerous to the conservative elements in society.

    I had some friends that would take a lot of MDMA in an outing, up to a full gram of it. I always thought this was dangerous, for the reasons stated above. It hypes up the body too much. I always took a little to mellow out my acid effects, to cause things to be a bit more lucid and "grounded". Funny to use such a term, huh?
  • Re: What are the dangers of MDMA?

    Tue, June 16, 2009 - 5:50 AM
    There's a significant body load with this one. This is a close chemical variant of methamphetamine - and while it has a much more benign and even healing effect on the psyche, its still a bit hard on the body. Especially compared to the phenyethylamine entheogens (LSD, psilocybin, DMT...) which have virtually no body load at all. I'd say once or twice a month, at the most.

    MDMA does tend towards addiction and abuse, I think that is pretty clear by now. So you need to have the right motivations for using it to know what the right frequency is. Seems like you do, so just listen to that.

    There's been some research to suggest that long-term use can damage the nervous system, especially the serotonin receptors on the nerve cells. I think I've seen this in people I know. I believe it can be healed in time, but it takes awhile - antidepressant drugs or supplements of L-Tryptophan can help. MDMA is a positive, healing chemical - just needs to be treated with respect and care.

    Whatever happened to mescaline? :D
    • Re: What are the dangers of MDMA?

      Tue, June 16, 2009 - 9:21 AM
      um actually LSD, Psilocybin, and DMT are in the the tryptamine group while MDMA is a Phen. Just sayin...

      www.erowid.org/psychoacti...rnal2.shtml
      • Re: What are the dangers of MDMA?

        Tue, June 30, 2009 - 4:56 PM
        I didnt think acid was a tryptamine. Are you sure about that? I know shrooms and DMT are. LSD is an indole ring.
        • Re: What are the dangers of MDMA?

          Mon, July 20, 2009 - 4:48 PM
          Yeah, LSD is a bit of an odd one to classify, It shares an indole ring like that of the tryptamines, but is encased in a much larger structure.
          The correct term for these class of compounds are ergolines.

          en.wikipedia.org/wiki/Ergoline

          As for MDMA, probably the main danger (excluding rare fatalities) is neurotoxicity.
          Quite a few scientists argue that this is only a real danger in large quantities and can be eliminated by correct dosing, proper hydration, and keeping cool.
          Others claim that while it may cause harm, this is only temporary and the brain "fixes" itself in a period of about 3-6 months.
          Finally you have the ones that say it's toxic in normal doses, and that permanent neurotoxicity can't be avoided.

          The main culprit for this is said to be the large release of dopamine (due to it's amphetamine like structure) which one, heats up the body to the point where brain damage may take place, and two, becomes toxic to the serotonin floating about in-between the synapses that can't find it's way back in because of MDMA's SRI effect.
          With that said, it's probably not a good idea to take MDMA with any other dopamine releasing chems such as amphetamines, cathines, piperazines, and cocaine.

          I've taken a fair amount of MDMA and i've not noticed any permanent damage, but I have a few friends that used to be proper pill heads who are now quite sketchy, have pretty odd mood swings, as well as poor shot term memory.
          It's worth pointing out that they also took a number of other drugs in combination with MDMA which no doubt also played a role.

          If that puts you off, there are a number of analogues out there which seem to be a lot safer, although as a result they don't quite have the "magic" of MDMA.
          They come pretty damn close though...

          Methylone and Butylone are both good examples, they're both currently thought to be a lot safer as well as legal.

          And if you want really safe (non neurotoxic) MDAI is your best bet, and technically legal.

          All can be brought online if you know where to look. ;)

          en.wikipedia.org/wiki/5,6-...minoindane

          en.wikipedia.org/wiki/Bk-MBDB

          en.wikipedia.org/wiki/MDMA

          en.wikipedia.org/wiki/Meth...hcathinone




  • D
    D
    online 103

    Re: What are the dangers of MDMA?

    Tue, June 16, 2009 - 7:13 AM
    wouldn't touch it because it is manmade

    but that having been said, it may have a place strickly for working on relationship - in other words, for working on relationship stuff, it would be worth the risk to me but then taken only with good intentions and only as few times as is necessary

    i know a lot of people would disagree but I stick with Terence on this one - stay with substances that have been vetted by millions of years of natural selection on this planet, period - manmade drugs are like playing Russian Roulette, if you're into that!
    • Re: What are the dangers of MDMA?

      Wed, June 17, 2009 - 2:04 PM
      "wouldn't touch it because it is manmade"
      Come on D!!! We all know Alex Shulgin is god!
      • B-b
        B-b
        offline 7

        Re: What are the dangers of MDMA?

        Wed, June 17, 2009 - 4:11 PM
        A molecule is a molecule. But some don't work in the human body all that well.

        I would like to see an article describing why it is that organically-derived molecules are more "godly" than artificial, man-made ones.

        Shit, I'd snort baking soda right now if it had any effects. That's how bored I am...
        • D
          D
          online 103

          Re: What are the dangers of MDMA?

          Wed, June 17, 2009 - 5:16 PM
          we'll see pretty soon I think how godly or ungodly machine consciousness is? Our collective baby, man-made consciousness
          • B-b
            B-b
            offline 7

            Re: What are the dangers of MDMA?

            Wed, June 17, 2009 - 5:38 PM
            I was making a joke based on the vegan's set idea of some things having gone through "longer trials" than others.

            Is man a mistake? Are man-made products a mistake? Certainly when we mess with the genome of plants we do damage, but over the long term, hybridization should get those "lucky charms" out of the wheat, or whatever else.

            Hasty chemists. But like I say, does toothpaste have psychedelic effects if you rub it on your gums?

            I remember Don Juan of Castaneda's book remarking about how evil a "woman" (in some way) Jimson weed was.

            That's around here, and I just might get bored enough to pull out the book and follow the recipe.
            • Unsu...
               

              Re: What are the dangers of MDMA?

              Wed, June 17, 2009 - 5:45 PM
              bob, before you go messing with datura, please read this link.

              www.dmt-nexus.com/forum/default.aspx

              Datura stramonium seeds

              Total alkaloid content: 0.1-0.7% tropane alkaloids. The average seed contains 0.3%.
              Seed weight: approximately 8 mg.
              Active alkaloids: hyoscyamine (approximately 80%), scopolamine (approximately 19%) with traces of atropine
              Average alkaloid content per seed: approximately 25 micrograms of tropane alkaloids.
              Typical safe dosage range: 1-10 seeds is preferred with 26 seeds being the absolute maximum safe dosage

              Datura stramonium seeds have some very valuable uses in the safe dosage range. The seeds are usually preferred because their alkaloid content is not as variable as the rest of the plant and so safe effective doses can more easily be measured.

              Relief Of Psychedelic Induced Nausea
              Tests done by a few SWIMs have shown that 1-3 seeds can completely block the nausea caused by the following psychedelic drugs:

              * Oral mescaline. For 1 SWIM, 3 seeds completely blocked the nausea of 300 mg mescaline.
              * Oral bufotenine. SWIM found 2 seeds effectively blocked the nausea of 100 mg oral bufotenine. SWIM normally gets tons of nausea from 100 mg of oral bufotenine.
              * Pharmahusca. For a few SWIMs, 1 seed blocked the nausea, but eventually there was a purge anyway. Details of this trip are found below in this thread.

              Potentiation of Psychedelics
              Tests done by a few SWIMs have shown 1-3 seeds can potentiate the effects of the following psychedelics:

              * Bufotenine. It increases the visuals slightly, and makes it slightly stronger.
              * LSA. It makes it more LSD-like and seems to improve the visuals and makes it almost twice as strong.
              * Mescaline. It alters the experience somewhat making it sort of LSD-like and makes it about twice as strong. SWIM experiences extreme euphoria from this combination, but some other SWIM’s have not.
              * Pharmahusca. It's said to make the visuals more LSD-like and make the trip a little more relaxed. Details of this trip are found below in this thread.




              If you take more than what 69ron has researched
              you will be very
              very
              sorry...

            • D
              D
              online 103

              Re: What are the dangers of MDMA?

              Wed, June 17, 2009 - 5:56 PM
              i think we are a mistake in a way - DNA evolving into ... us

              considering how old DNA is, how could any entity less than a god know that human consciousness would evolve billions of years in the future?

              I think DNA was seeded by not a god but an entity perhaps not DNA based at all - perhaps not even from this dimension at all? And the intelligence that seeded what we were to become, what become of ... our parents? Talking 4 billion years and another dimension, doubt they are still "alive"

              Then there is the fact that it appear core DNA could be virtually as old as life on the planet - meaning, among other things of course, that this core DNA is more stable than continents, stronger than miles of rock, more enduring than diamonds . . . crazy man
          • B-b
            B-b
            offline 7

            Re: What are the dangers of MDMA?

            Wed, June 17, 2009 - 5:38 PM
            Ever read Kurzweil?
            • D
              D
              online 103

              Re: What are the dangers of MDMA?

              Wed, June 17, 2009 - 6:07 PM
              o yea age of spiritual machines and singularity - that was the "universal" message this New Creature gave, "if you connect the mind of man to the mind of machine before connecting the mind of man to the mind of plant, the biosphere is doomed". That is all about this singularity which I think is really close

              we are about to create an intelligent machine that is conscious and this new consciousness is what the New Creature warns of - since we create it, it will not have any more wisdom than we possess but it will have much more intelligence, and in effect, we create a monster of logic, an abomination of frankenstein nature, and this new consciousness will go on to not only kill us all ala Terminatro but ulitimately destroy all DNA from the deepest rocks in the planet the highest levels of the atmosphere

              The plant mind and the Gaian mother need our help to prevent this - need our "hands" - nuts sounding I know but they do not have anything like hands. The great Gaian mother of us and the Plant Mind of the planet recognize our human consciousness as a power on this planet and they offer their alliance to prevent this tragedy of tragedies
    • Re: What are the dangers of MDMA?

      Wed, July 22, 2009 - 11:52 AM
      "wouldn't touch it because it is manmade"

      Just noticed this, I find that argument a bit silly personally.
      Especially considering that Skunk 1 in your profile picture is a man made cannabis hybrid...
  • Re: What are the dangers of MDMA?

    Tue, July 21, 2009 - 6:35 AM
    Some guy I know sells it in gram bags for $60. I was tempted but a good friend told me that's the last thing I need for my mechanical heart valve. lol If I cant do blow anymore I guess I should assume I should stay away from MDMA too unfortunately. And ecstasy. Too bad. I can get X for 6 bux too.

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